VP, Head of Commercial Operations

Patients with adenoid cystic carcinoma (ACC) have waited decades for a treatment option. At Remix Therapeutics, we intend to change that. We are a clinical-stage biopharmaceutical company that has pioneered a new class of small molecule medicines targeting the RNA splicing machinery — correcting the disease-causing errors that drive ACC and other serious conditions at their source. REM-422 is our lead program, currently in clinical evaluation for ACC and AML/HR-MDS, and it is at a critical inflection point. Remix is building the team to bring this novel molecule forward for patients. Position Summary: Remix is seeking an experienced, strategic and hands-on Vice President, Head of Commercial Operations to build and lead the company's Commercial Operations and Business Insights function, initially focused on REM-422. This executive will be accountable for forecasting, market research and competitive intelligence; commercial data and analytics; CRM and field technology; sales operations; incentive compensation; performance reporting; and the external partner ecosystem required to support launch. Reporting to the Chief Commercial Officer and partnering closely with the Head of Sales & Marketing, Head of Market Access, Finance, IT, Legal and Compliance, this leader will translate commercial strategy into disciplined operating plans, high-quality decisions and scalable execution. The successful candidate will pair strategic judgment with analytical depth and a willingness to work directly in the details - from patient-based forecasting and vendor selection to field force design, and dashboard development. Key Responsibilities: Business Insights, Forecasting & Competitive Intelligence Set and lead the enterprise commercial insights agenda, integrating primary and secondary market research, epidemiology, patient journey and treatment-flow analysis, market sizing, customer insights and competitive intelligence. Build, maintain and communicate patient-based forecasts for ACC and future indications; partner with Finance on revenue scenarios, long-range planning and sensitivity analyses. Translate clinical and regulatory outcomes, target product profile assumptions, biomarker prevalence, treatment patterns, market access dynamics and competitive developments into clear commercial implications. Develop a sequenced learning plan that addresses the highest-value uncertainties for indication prioritization, positioning, go-to-market design, field planning, access strategy and lifecycle management. Create compliant mechanisms to capture and synthesize insights from customers, field teams, patient services, payers, external experts and data sources, then convert those insights into decisions and action. Support portfolio strategy, business development and new-product planning through commercial opportunity assessments, analog analyses and scenario modeling. Commercial Data, Analytics & Technology Develop a phase-appropriate commercial data and analytics roadmap that supports pre-launch decisions, launch execution and post-launch performance management. Select, integrate and govern data from market research, claims, specialty pharmacy and distribution, patient services, market access, CRM, finance and other sources to create a reliable commercial source of truth. Design and implement the commercial technology stack, including CRM, business intelligence and dashboarding, data integration, customer master data, affiliations and account hierarchies. Establish data governance, quality standards, access controls, privacy and compliance requirements, vendor service levels and documentation in partnership with IT, Legal and Compliance. Build decision-oriented dashboards and reporting for executive leadership and commercial teams, balancing leading indicators, launch-readiness metrics and business outcomes. Manage commercial data, analytics and technology partners, ensuring fit-for-purpose solutions, disciplined budgets, strong performance and scalable…