Vice President, Market Access

MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we’re looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY — The Vice President, Market Access is responsible for developing and executing Mirum's North American Market Access strategy to optimize patient access, reimbursement, and sustainable portfolio value across all commercial products and pipeline assets. As a member of the Commercial Leadership Team, this executive partners closely with Medical Affairs, Commercial, Finance, Legal, Regulatory, Commercial Operations, and Global colleagues to ensure market access strategies are integrated across the product lifecycle. The Vice President provides strategic leadership across Pricing & Contracting, National and Regional Payer Accounts, Field Reimbursement, and Health Economics & Outcomes Research (HEOR). This leader is accountable for maximizing patient access while achieving net revenue objectives through innovative payer strategies, pricing excellence, evidence generation, and cross-functional execution. This role is responsible for building and developing a high-performing Market Access organization, influencing enterprise strategy, and serving as Mirum's senior market access expert with executive leadership, customers, and external stakeholders. JOB FUNCTIONS Strategic Leadership Develop and execute Mirum's North American Market Access strategy in alignment with corporate and commercial objectives across marketed products and pipeline assets. Serve as the executive leader responsible for maximizing patient access while achieving net revenue, reimbursement, and profitability objectives. Provide strategic counsel to the Executive Leadership Team on evolving payer dynamics, pricing strategy, reimbursement trends, healthcare policy, and competitive market developments. Lead market access planning for pipeline products, lifecycle management initiatives, label expansions, and commercial launch readiness. Pricing, Contracting & Market Access Strategy Own enterprise pricing strategy, gross-to-net optimization, contracting strategy, and reimbursement economics across commercial and government channels. Accountable for compliant commercial pricing, government price reporting, rebate administration, and associated financial obligations. Establish annual pricing governance and contracting strategies that optimize market access while achieving corporate financial objectives. Lead payer contracting strategies that balance coverage objectives, reimbursement quality, and net price performance. Payer Strategy Lead national and regional payer account strategies to secure optimal coverage, reimbursement, utilization management policies, and patient access across Commercial, Medicare, Medicaid, and other government programs. Provide leadership to the field-based payer account and field reimbursement organizations to achieve strategic objectives related to access, reimbursement, and customer engagement. Health Economics & Outcomes Research (HEOR) Partner with Medical Affairs, Biostatistics, and Global Market Access to establish evidence generation priorities, HEOR strategy, and payer evidence plans supporting the value proposition across the Mirum portfolio. Ensure timely development and submission of US and Canadian payer dossiers aligned with global value messaging and reimbursement objectives. External Engagement & Policy Develop sustainable external communication strategies supporting reimbursement, label expansions, future indications, and pipeline products. Monitor evolving federal and state healthcare policy, including Medicare, Medicaid, 340B, Inflation Reduction Act (IRA), and reimbursement changes, e…