Software Engineer III, Voice AI

Position Summary Are you ready to make a real impact on people's lives and be part of a rapidly-growing team? Natera is seeking a Software Engineer III to help design, develop, and maintain our Voice AI platform. This platform handles thousands of patient calls daily, providing automated test status, identity verification, billing support, and intelligent routing — directly improving patient access to their genetic testing results. Join us in our mission to change the way disease is managed, and be a part of a dedicated group of professionals who are passionate about making a difference. The Software Engineer III – Voice AI is responsible for building and maintaining the real-time conversational AI systems that power Natera's automated patient call center. This role requires strong expertise in TypeScript and Node.js, hands-on experience with voice AI pipelines (STT, LLM orchestration, TTS), and familiarity with telephony systems, agentic architectures, and event-driven design. You should be comfortable working with real-time audio streaming, WebSocket protocols, and the unique latency and UX challenges of voice-based AI. You'll collaborate with cross-functional teams in a fast-paced environment to ship features that measurably improve call efficacy and patient satisfaction. Primary Responsibilities Lead Take ownership of assigned voice AI features and components, guiding them through the full software development lifecycle. Contribute to design discussions, code reviews, and best practice adoption within the Voice AI team. Drive technical decisions on voice pipeline optimization — VAD tuning, turn-taking, interruption handling, and latency management. Manage Plan and prioritize tasks in an Agile environment, ensuring timely and high-quality delivery. Work with Product Managers and stakeholders to refine requirements and scope technical efforts for conversational AI features. Monitor voice platform health metrics (call efficacy, ASR accuracy, per-segment latency) and prioritize improvements based on data. Nurture Mentor junior team members, sharing knowledge and best practices in voice AI architecture, TypeScript, and real-time systems. Encourage a culture of continuous learning and technical excellence through pair programming and design reviews. Document voice AI patterns, integration contracts, and operational runbooks for the team. Collaborate Partner with Product Managers, QA, and clinical operations to gather requirements, validate conversational designs, and guide projects from inception to deployment. Coordinate with other engineering teams to integrate voice agents with internal services via authenticated APIs. Work with the analytics team to ensure voice metrics flow correctly through the data pipeline for reporting and optimization. Effect Change Drive improvements in our multi-agent orchestration approach — tool calling patterns, agent handoff logic, and state management across conversation turns. Advocate for high-quality standards and automated testing strategies for conversational AI systems, including voice-specific test patterns (simulated calls, transcript validation, latency benchmarks). Identify and resolve voice-specific UX issues: ASR errors on medical terminology, silence detection tuning, barge-in recovery, and end-to-end response latency. Qualifications 5+ years of overall software development experience, focusing on scalable backend services using Node.js and TypeScript. 1+ years of experience with voice AI, conversational AI, or real-time audio systems in production. Hands-on experience with agentic LLM architectures — tool calling, multi-agent orchestration, prompt engineering, and conversation state management. Familiarity with voice AI pipeline components: STT (Deepgram, Azure Speech, OpenAI Whisper), TTS (ElevenLabs, OpenAI, Cartesia), and LLM APIs (OpenAI Realtime API, Anthropic Claude). Experience with telephony systems — Twilio (media streams, SIP, IVR) or equivalent WebSocket-based audio str…