Senior Technical Specialist, Engineering and Facilities

Company Overview: Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform with integrated gene editing, delivery and internal manufacturing capabilities. Beam’s suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. This has the potential to enable a wide range of therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs. Beam is a values-driven organization committed to its people, cutting-edge science, and a vision of providing life-long cures to patients suffering from serious diseases. Position Overview: The Senior Technical Specialist, Engineering and Facilities will report directly to the Sr. Director of Engineering & Facilities. Operating as a highly visible, cross-functional individual contributor under a centralized Shared Services Model, this role serves as the primary technical and engineering document resource across all four core pillars of the department: Capital Projects, Process Engineering, Automation & Controls, and Facilities & Maintenance. This position will be critical to the operational readiness and sustainable compliance of our infrastructure for commercial operations. The Senior Technical Specialist will author, review, and champion complex lifecycle quality events and engineering documentation, acting as a collaborative bridge between Engineering, Manufacturing Operations, Process Development, Quality Control, and Quality Assurance. This role is ideally suited for a high-performing technical professional looking to maximize their organizational impact as an individual contributor, with a structured pathway to scale into a formal engineering management role as commercial operations expand. Responsibilities: Centralized Documentation Authoring: Support the entire Engineering & Facilities team by authoring, reviewing, and shepherding critical technical documents—including engineering studies, technical summaries, user requirement specifications (URS), functional specifications, and validation/engineering turn-over packages (ETOP)—ensuring cross-functional alignment across all product lines Lifecycle Quality Events: Initiate, investigate, and drive to completion engineering-related deviations, Corrective and Preventive Actions (CAPAs), and complex Engineering Change Controls (ECC) to meet stringent internal procedures and regulatory expectations Advanced Root Cause Analysis: Lead technical investigations for facility-wide and equipment-specific issues (e.g., clean utility continuous monitoring alerts, HVAC excursions, or automated process equipment failures during a run) using formal root cause analysis tools Cross-Functional Liaison: Act as a main point of contact with our Process Engineering team to translate clinical-scale process parameters from the Process Development and MS&T teams into commercial engineering requirements, while partnering with Manufacturing Operations to minimize impact on production schedules Risk Management & Quality by Design: Facilitate and document Quality Risk Management (QRM) assessments and Failure Mode and Effects Analyses (FMEAs) to ensure robust quality and cross-contamination mitigations are built into multi-modality engineering assets from the beginning Standard Operating Procedures: Draft, review, and optimize engineering, maintenance, and calibration SOPs as the site advances its commercial operational readiness Audit Readiness & Defense: Maintain all engineering lifecycle documentation in an inspection-ready state, serving as a subject matter expert (SME) to defend technical engineering studies and deviation histories during internal and external health authority audits Operational…