Senior Director, Corporate Strategy - Prolaio

About Us Kardigan is a heart health company working to make cardiovascular disease preventable, curable and no longer the leading cause of death in the world. It is Kardigan’s mission to develop multiple targeted treatments in parallel that bring people with cardiovascular diseases to the cures they deserve. Led by Tassos Gianakakos, Jay Edelberg, M.D., Ph.D., and Bob McDowell, Ph.D., Kardigan’s co-founders have reunited after leading MyoKardia to discover and develop mavacamten, the first cardiac myosin inhibitor, resulting in an acquisition by Bristol Myers Squibb in 2020. We have a cutting-edge discovery and translational research platform, a pipeline of late-stage candidates, and an industry-leading team that is driven to improve the lives of patients. At Kardigan, we are motivated by our values which guide how we work, interact, and achieve our goals. Driven by patients and their families , we are deeply committed to improving the lives of patients and prioritizing their needs above all else. We believe in being authentic —leading with truth to bring out the best in others by creating an environment where every person knows they will be fully accepted. With an eagerness to learn , we encourage the highest levels of curiosity and are open to changing our minds. We are committed to winning as a team with urgency, excellence, and intention, and support each other no matter what role we play or where we sit. Lastly, we strive to enable the impossible because patients are counting on us. We are not afraid to take risks to unlock innovation and advance scientific discoveries. These values are the foundation of our work, empowering us to make a real difference, every day. This position is based in Chicago and dedicated to supporting Prolaio, a wholly owned subsidiary of Kardigan. Prolaio is a patient-centered clinical intelligence company dedicated to advancing today’s cardiology research and care with real-world patient data and insights. The company was created by cardiologists and cardiovascular scientists specifically to address the world’s number one cause of death, cardiovascular disease. Its FDA-cleared software integrates real-world clinical data and proprietary algorithms to deliver outcome-driven insights to empower patients, researchers, physicians, and product leaders. By combining scientific rigor with cutting-edge technology, Prolaio aims to expedite clinical trials and improve patient outcomes across cardiology therapeutic areas. Position Title: Senior Director, Corporate Strategy - Prolaio Department: Corporate Strategy Primary Reporting Line: Vice President, Corporate Strategy, Kardigan Secondary Reporting Line: General Manager, Prolaio Location: Chicago, IL – On-site 4 days per week (Mon to Thurs) Job Overview: The Senior Director, Corporate Strategy – Prolaio is a senior individual contributor role dedicated to Prolaio, a wholly owned subsidiary of Kardigan. This position will play a central role in shaping and executing Prolaio’s company strategy, leading high ‑ impact strategic initiatives, and supporting pricing, partnerships, and business development efforts across Prolaio’s clinical research and care delivery offerings. While the role sits within Kardigan’s Corporate Strategy function and reports to the Vice President of Corporate Strategy, it operates day ‑ to ‑ day as a dedicated strategic leader for Prolaio, working in close partnership with the Prolaio General Manager and leadership team. The role serves as a strategic bridge between Kardigan and Prolaio, ensuring alignment with enterprise priorities while enabling Prolaio to operate with speed, focus, and strategic independence. This role focuses on framing Prolaio’s most critical strategic questions; conducting market landscaping, market research, and market sizing; shaping pricing and monetization strategies; developing business cases and financial analyses for new growth opportunities; and driving execution across complex, cross ‑ functional init…