Research Associate, Gene Engineering and Delivery

**Working with Us** Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: https://careers.bms.com/working-with-us. The Cell Therapy Thematic Research Center is one of BMS’s differentiated research platforms delivering innovative therapies to patients. Our mission is to drive leadership in the use of cellular therapies to harness the power of the immune system in treating hematologic malignancies, solid cancers, and autoimmune disease. More specifically, our discovery and translational scientists are focused on developing next-generation, engineered cell-based therapies. The team is committed to discovering and developing transformative therapies that harness the power of the immune system to improve patient outcomes. **Position Summary** The Gene Engineering and Delivery team in the Cell Therapy Thematic Research Center is seeking a highly motivated scientist to advance next-generation cancer immunotherapies through molecular design, viral vector engineering, and gene delivery innovation. This role will focus on designing, cloning, characterizing, and producing vector constructs that enable development of CAR T cell therapies. The ideal candidate brings strong molecular biology skills, hands-on cell culture experience, and a collaborative, problem-solving mindset in a fast-paced research environment. **Key Deliverables** - Execute molecular design and cloning of complex DNA constructs for cell therapy applications. - Demonstrate competency in mammalian cell culture, transfection, and transduction of primary T cells. - Execute molecular engineering designs and assays that support gene delivery and viral vector characterization. - Produce viral vectors to enable gene delivery workflows and experimental evaluation. **Key Responsibilities** In the role as a Research Associate within the Gene Engineering and Delivery team, the ideal candidate will: - Design and clone DNA constructs to support CAR T cell therapy development. - Culture mammalian cell lines for viral vector production, assessment, and gene delivery applications. - Set up and run molecular characterization and cellular assays to evaluate viral vector performance. - Execute viral vector production and characterization protocols. - Collaborate with team members to assess the technical feasibility of novel gene delivery methods. - Process and analyze data, review results, and communicate conclusions clearly. - Maintain accurate, detailed electronic laboratory notebook records and supporting documentation. - Summarize and present data in group meetings and written reports. - Work cross-functionally to execute and improve experiments and assay performance. **EXPERIENCE** **Basic Qualifications** - Bachelor’s Degree **Preferred Qualifications** - B.S./B.A. degree in a scientific discipline and 2+ years of hands-on experience in relevant field of research - Strong molecular biology skills, including molecular assay development, molecular design and cloning of complex DNA constructs, PCR, RT-PCR, and mRNA and DNA preparation. - Experience with tissue culture techniques, including transfection of mammalian cell lines and transduction of T cells. - Excellent organization, time manag…