Postdoctoral Research Associate - Pathology & Immunology

# **Position Summary** We have an exciting opportunity for an enthusiastic, driven and creative Postdoctoral Research Associate to join the laboratory of Dr Aydan Szeto with the department of Pathology & Immunology at WashU in St. Louis to discover new pathways in the regulation of type-2 immunity. We have recently used cutting-edge CRISPR screens to identify new regulators of ILC2 and Th2 cell function and produced the first ‘Boolean mouse’ to study ILC2s in vivo (Science 2024 PMID 38935708; Nature Immunol. 2023 PMID 36550322; Immunity 2023 PMID 37285842). You will be able to take advantage of these exciting new techniques and tools to make significant contributions to our fundamental understanding of type-2 immunity. You will initially work closely with Dr Aydan Szeto but have the opportunity to work independently to plan your own work and objectives. The appointment is viewed as a training or transitional period preparatory to an academic, industrial, governmental, or other full-time research or teaching career. Used when the appointee performs specific services on a grant or contract in exchange for compensation. # **Job Description** **Primary Duties & Responsibilities:** Information on being a postdoc at WashU in St. Louis can be found at https://postdoc.wustl.edu/prospective-postdocs-2/. Trains under the supervision of a faculty mentor including (but not limited to): - To foster a passion for scientific discovery and to lead a research project aimed at discovering new biology of ILC2s and Th2 cells. - To identify, develop and apply a broad range of techniques to pursue the research objectives. - To draft scientific papers, and contribute to the overall preparation of research for publication. - To assist in the training of PhD and undergraduate students. **Working Conditions:** This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals. **Salary Range:** Base pay is commensurate with experience. **Applicant Special Instructions:** Interested candidates should submit a cover letter\*, CV, and 3 letters of recommendation to Aydan Szeto at szeto@wustl.edu. \*Some of the following experience would be particularly useful. Please list the relevant experience in the cover letter. - Extensive experience in immunology. - In-depth knowledge of human and/or mouse immune cell function. - Knowledge and/or experience in high dimensional and conventional flow cytometry. - Mouse handling and tissue processing. - Generation and analysis of bulk and/or single cell transcriptomic data. - Computational and bioinformatic skills. - Experience in microscopy. - Generation and analysis of mouse models. - Handling of human samples. - Molecular biology skills including CRISPR, cloning and qPCR. - In vitro cell culture including primary immune cells. - Experience with retroviral, lentiviral and AAV transduction. The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time. # **Required Qualifications** **Education:** Ph.D., M.D. Or Equivalent Terminal Or Doctoral Degree. **Certifications** **/Professional Licenses** **:** No specific certification/professional license is required for this position. **Work Experience:** No specific work experience is required for this position. **Skills:** Not Applicable **Driver's License:** A driver's license is not required for this position. # **More About This Job** **At WashU, postdoctoral appointments:** - Have a 5-year term limit that includes previous experience. # **Preferred Qualifications** **Education:** No additional education unless stated elsewhere in the job posting. **Certifi…