Head, Business Operations and Alliance Management

Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life-threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy through a portfolio of innovative technologies, including autologous, allogeneic, and in vivo cell therapy approaches. Our research spans chimeric antigen receptor T-cell (CAR-T), T-cell receptor (TCR-T), natural killer (NK) cell-based therapies, and other emerging platforms designed to transform the treatment of serious diseases. From our global network of research and development sites, we are committed to discovering and developing safe, effective, and cutting-edge therapies for patients worldwide. Legend Biotech entered into a global collaboration agreement with Johnson & Johnson to jointly develop and commercialize CARVYKTI® (ciltacabtagene autoleucel; cilta-cel). Through this strategic partnership, we combine complementary expertise and capabilities to advance innovative immunotherapies for patients living with multiple myeloma. Legend Biotech is seeking a Head, Business Operations and Alliance Management as part of the Commercial team based in Bridgewater, NJ. Role Overview Reporting directly to the President, Carvykti BU, this role serves as the BU’s Strategy & Execution Lead, driving alignment, execution, and operational effectiveness across Commercial, GMS, Quality, and Medical Affairs. A core responsibility is managing Legend’s strategic alliances—ensuring strong governance, seamless communication, and proactive issue resolution so both organizations deliver on joint CAR‑T objectives. The role also leads BU‑wide engagement and communication, fostering clarity, connection, and cultural cohesion across global teams. In parallel, it drives capability building, strengthening organizational readiness, talent development, and cross‑functional effectiveness to support Carvykti’s rapid growth and strategic priorities. Key Responsibilities Lead governance of current and future alliances, ensuring transparent communication, shared accountability, and timely escalation. Coordinate joint steering committees, joint working teams, and governance bodies to ensure compliance with collaboration agreements and delivery on shared milestones. Maintain a strong relationship with partner organizations (e.g., Janssen) and serve as a central connective point between Carvykti BU functional stakeholders and alliance partners. Proactively identify risks, misalignments, or emerging strategic opportunities within collaborations and drive resolution or acceleration initiatives. Ensure open communication channels across both organizations and consistent partnership health tracking. Drive engagement initiatives and forums - town halls, BU business reviews, culture initiatives, leader communications, and cross‑functional alignment sessions. Serve as a strategic advisor to the BU President on messaging, engagement cadence, and organizational pulse. Design and lead BU‑level internal communications strategy, ensuring clarity, transparency, and alignment from the President through LT‑1 and field/operational teams. Partner with BU President & LT to shape and drive BU strategic initiatives, including transformation, digital capability scaling, operational innovation, and cross‑functional initiatives. Monitor industry trends (CAR‑T evolution, regulatory updates, partnership models) and translate insights into BU priorities. Support BU‑wide capability strategy (technical, leadership, and operational), to ensure teams are equipped for current and future needs across Commercial, GMS, Quality, and Medical Affairs. Build mechanisms to measure capability maturity and organizational effectiveness. Partner with HRBP, OD, and Functional Heads to design learning ecosystems and talent acceleration pathways. The Head, Business Operations and Alliance Mgmt. exercises independent decision-making authority across strategic and operational domains, including p…