Clinical Science Liaison (CSL)

Summary Precision BioSciences is advancing PBGENE-DMD, a first-in-class ARCUS gene editing therapy that directly corrects the dystrophin gene. Following our recent FDA Fast Track designation, we are accelerating the mission to deliver this transformative treatment to patients with Duchenne Muscular Dystrophy (DMD). To support this milestone, we are seeking a Clinical Science Liaison (CSL). This newly created, field-based role will interface on an ongoing basis with Clinical Operations, Medical Affairs, and Patient Advocacy, serving as the primary external representative to clinical trial sites, investigators, and the advocacy community for the FUNCTION-DMD program. Essential Duties and Responsibilities Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of this position. This list contains the major duties and requirements of the job and is not all-inclusive. Incumbent(s) may be expected to perform role-related duties other than those contained in this document. 1. Clinical Site Management & Training Serve as a primary scientific interface site-level contact for investigators and site medical staff within responsible geography, liaising with Clinical Operations, the CRO and the Medical Monitor who maintain primary contacts for site operations, monitoring and clinical trial issue resolution Be the local expert on PBGENE-DMD, the clinical trial protocol, and the process for administering drugs Lead site-level training on protocol procedures and staff support Thoroughly understand the patient journey in the trial at the clinical site and work with and through the staff to facilitate improvements at the site that will help the patient and family continue in the trial Meet with all staff who will be assessing patients to ensure consistency with assessments; Ensure training of new staff members Educate staff about PBGENE-DMD; Train fellows & residents that cycle through the clinical site. Support biopsy training coordination alongside Clinical Operations Support site-level understanding of protocol and data to be collected for the trial; Note: Data quality and input are the responsibility of Clinical Operations and Data Management Support site staff understanding of protocol amendments to ensure all appropriate changes developed by Clinical Operations, the Medical Monitor and Clinical Development are implemented at the site Triage scientific and protocol-related questions directing safety, eligibility, dosing, patient-specific, and/or medical judgement questions to the Precision Medical Monitor and/or Clinical Development Provide frequent updates to Clinical team to support ongoing recruitment Bring Precision personnel to the site as needed to facilitate the relationship at all levels Be onsite during each administration of PBGENE-DMD during Phase1/2 2. Scientific Exchange & Medical Affairs Have keen awareness of competing trials underway at the site and help site level decision-makers and parents understand the rationale for choosing a gene editing approach Provide literature summaries and interpret external data trends for internal teams Gather and relay investigator scientific feedback to Clinical Development leadership Provide background on standard-of-care shifts in the DMD treatment landscape Support Data and Safety Monitoring Board (DSMB) meeting preparation as needed Translate complex ARCUS gene editing science into accessible language for non-scientific audiences Articulate Precision�s differentiation versus AAV gene therapy and exon-skipping approaches Attend scientific and medical conferences to represent Precision BioSciences 3. Patient Advocacy & Community Engagement Partner with Clinical Development, Clinical Operations, Program Management and Corporate Communications team to support compliant scientific education for advocacy organizations and patient communities Support the presentation of the PBGENE-DMD program to advocacy groups at all levels: National (…