Bioinformatic Scientist

## Thanks for your interest in Children's Mercy! Do you envision finding a meaningful role with an inclusive and compassionate team? At Children’s Mercy, we believe in making a difference in the lives of all children and shining a light of hope to the patients and families we serve. Our employees make the difference, which is why we have been recognized by U.S. News & World Report as a top pediatric hospital, for eleven consecutive years. Children’s Mercy is in the heart of Kansas City – a metro abounding in cultural experiences, vibrant communities and thriving businesses. This is where our patients and families live, work and play. This is a community that has embraced our hospital and we strive to say thanks by giving back. As a leader in children’s health, we engage in meaningful programs and partnerships throughout the region so that we can improve the lives of children beyond the walls of our hospital. ## Overview The Children’s Mercy Research Institute (CMRI) is seeking a highly skilled and motivated Bioinformatics Scientist with a strong specialization in Gene Therapy and Advanced Therapeutics to join the Yue Xu Lab. This position is tailored for a computational powerhouse eager to apply advanced data science, next-generation sequencing (NGS) workflows, and predictive modeling to further the genetic medicine, translational oncology, and pediatric therapeutic goals of CMRI. The Yue Xu Lab operates at the cutting edge of AI for Science, specializing in the development of deep learning-powered platforms (such as AGILE and LUMI-lab) that automate and accelerate the discovery and rational engineering of ionizable lipid nanoparticles (LNPs) for mRNA, circular RNA, and plasmid DNA delivery. By merging active machine learning with high-throughput combinatorial chemistry, the lab constructs organ-selective and tumor-tailored nucleic acid delivery systems to achieve targeted gene correction, inhaled base editing, and enhanced cancer immunotherapies. The Bioinformatics Scientist will take computational ownership of the lab's multi-omic pipelines and predictive modeling architectures. You will work closely with wet-lab researchers to bridge AI-driven vector design with experimental validation, translating high-dimensional genomics data into optimized molecular therapeutics against major pediatric diseases. At Children’s Mercy, we are committed to ensuring that everyone feels welcomed within our walls. A successful candidate for this position will join us as we strive to create a workplace that reflects the community we serve, as well as our core values of kindness, curiosity, inclusion, team and integrity. *Additionally, it’s important to us that we remain transparent with all potential job candidates. Because we value the safety of the patients and families we serve, as well as the Children’s Mercy staff, we want to let you know that the seasonal influenza vaccine is a condition of employment for all employees in our organization. New employees must be willing to be vaccinated if found non-immune to measles, mumps, rubella (MMR) and chicken pox (varicella) and/or without evidence of tetanus, diphtheria, acellular pertussis (Tdap) vaccination since 2005. If you are selected for this position, you will be asked to supply your immunization records as proof of vaccination. If you and have any concerns about receiving these vaccines, medical and/or religious exemptions can be further discussed with Human Resources.* ## Responsibilities - Conduct original laboratory research under the supervision of the principal investigator. - Analyze research data and perform troubleshooting. - Prepare manuscripts and deliver presentations. ## Qualifications - Master's Degree Bioinformatics, Computer Science, Biostatistics, Computational Biology or Biology and No Experience necessary / On-the-Job Training Demonstrated skill and knowledge in specific requirements of position needed. or - Bachelor's Degree Bioinformatics, Computer Science, Biostatist…